So it appears, with a real minimum of information, that a human effective dose would be between 0.15 and 0.6 mg per kg or approximately 0.1 to 0.3 mg per pound. Because a withholding time in milk has not been established for this product, do not use in female sheep providing milk for human consumption. Release pressure on the container to avoid further filling. Avoid prolonged exposure above 25°C (77°F). In case of accidental skin contact and/or clothing contamination, wash skin thoroughly with soap and water and launder clothing with detergent. So it appears, with a real minimum of information, that a human effective dose would be between 0.15 and 0.6 mg per kg or approximately 0.1 to 0.3 mg per pound. This chapter discusses the adverse effects of antihelminthic drugs on the physiology of the human, such as albendazole, mebendazole, diethylcarbamazine, ivermectin, and levamisole. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. 4.6 out of 5 stars 14. … Do not overdose. CYDECTIN Long Acting Injection for Sheep Lambs/hoggets born in the previous spring are widely recognised as the highest risk group of sheep on New Zealand farms likely to suffer from worm effects. Moxidectin, also known as ProHeart®, is used primarily to prevent heartworm infection for dogs. To obtain a copy of the material safety data sheet (MSDS) which provides more detailed occupational safety information or to report adverse reactions attributable to exposure to this product, call 1-800-422-9874. Cydectin Pour-On when applied at the recommended dose level of 0.5 mg/2.2 lb (0.5 mg/kg) body weight is effective in the treatment and control of the following internal [adult and fourth-stage larvae (L4)] and external parasites of cattle: Ostertagia ostertagi - Adult and L4 (including inhibited larvae), Trichostrongylus colubriformis - Adult and L4, Psoroptes ovis (Psoroptes communis var. CYDECTIN Injectable, when administered at the recommended dose level of 0.2 mg/2.2 lb (0.2 mg/kg) body weight, is effective in the treatment and control of the following internal and external parasites of cattle: Gastrointestinal Roundworms Keep this and all drugs out of the reach of children. Please note: The injectable form of Moxidectin was taken off the market due to potential side effects in dogs however is back on the market after passing extensive FDA safety testing. In this study no signs of toxicity were seen in sheep given up to 5 times the recommended dose. Sites for administration of CYDECTIN Injectable. For most effective external parasite control, Cydectin Pour-On should be applied to all cattle in the herd. This effect may be more pronounced in … Cydectin Oral Drench for Sheep is a ready-to-use solution containing 0.1% moxidectin. That is within the dosing range tested in the clinical trial. Cydectin Triclamox Pour On is for the treatment of mixed trematode (fluke) and nematode (roundworm) infections and certain arthropod infestations. Avoid contaminating the drench solution. Due to the angular topline characteristic of most dairy breeds, it is recommended that all pour-on products be applied slowly to dairy cows. Free moxidectin may adversely affect fish and certain aquatic organisms. Cydectin Pour-On is effective against the migrating stage of cattle grubs (Hypoderma larvae). Keep this and all drugs out of the reach of children. Apply the recommended volume of Cydectin Pour-On evenly along the backline of the animal from the withers to the tailhead (see Figure 1). If ingested, increased salivation, tremors, vomiting, and decreased appetite can occur. The recommended rate of administration for CYDECTIN Oral Drench for Sheep is 1 mL per 11 lb (5 kg) body weight to provide 0.2 mg moxidectin/2.2 lb (0.2 mg/kg) body weight. ... Do not use in sick, debilitated, or underweight animals. Do not mix with any other products before administration. For optimal control of horn flies, the product should be used as part of an integrated control program utilizing other methods to provide extended control. It would be like a human trying to live on Mars. The recommended rate of administration for Cydectin 1% Oral Drench for Sheep is 1 mL per 11 lb (5 kg) body weight to provide 0.2 mg moxidectin/2.2 lb (0.2 mg/kg) body weight. We comply with the HONcode standard for trustworthy health information -. The product has a persistent effect in preventing re-infection by Ostertagia ostertagi and by Dictyocaulus viviparus for 5 weeks after a single dose. 4,916,154 - used under license. We can’t do it. The recommended rate of administration for Cydectin Oral Drench for Sheep is 1 mL per 11 lb (5 kg) body weight to provide 0.2 mg moxidectin/2.2 lb (0.2 mg/kg) body weight. Active Ingredient: Moxidectin, Triclabendazole. Do not use in sick, debilitated, or underweight animals. CYDECTIN (moxidectin) Pour-On is a ready-to-use topical formulation intended for direct application to the hair and skin in a narrow strip extending along the top of the back from the withers to the tailhead (see Figure 1). Cydectin LA acts by interfering with chloride channel-mediated neurotransmission in the parasite. That is within the dosing range tested in the clinical trial. Generic Name: moxidectin liquid Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Is ivermectin safe? Side effects increased as the dose was raised, so there is no sense in going crazy and using a higher dose. P.J.J. CYDECTIN Oral Drench for Sheep, when administered at the recommended dose level of 0.2 mg moxidectin/2.2 lb (0.2 mg/kg) body weight, is effective in the treatment and control of adult and larval (L 4) stages of the following internal parasites of sheep: Parasites. The table below will assist in the calculation of the appropriate volume of drench in 1.0 mL increments and it must be administered based on the weight of animal being treated. © 2010 Boehringer Ingelheim Vetmedica, Inc. All Rights Reserved. Protect from light. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. There are two main types of this disease in New Zealand cattle. For protection against severe challenge by Haemonchus contortus (barber’s pole worm) for up to 4 months. Keep this and all drugs out of the reach of children. Moxidectin binds selectively and with high affinity to glutamate-gated chloride ion channels which are critical to the function of invertebrate nerve and muscle cells. Cydectin Oral Drench for Sheep, when administered at the recommended dose level of 0.2 mg moxidectin/2.2 lb (0.2 mg/kg) body weight, is effective in the treatment and control of adult and larval (L4) stages of the following internal parasites of sheep: Oesophagostomum columbianum - Adult and L4, Trichostrongylus colubriformis - Adult and L4. So the vet jut was out and we did Cydectin Oral and big hit of ban amine. Dosage Form: FOR ANIMAL USE ONLY. Phone: (02)9899 0444 Page 2 of 4 Issued: 4 Jul 2002 Revision 5 ll HEALTH HAZARD DATA Health Effects: No specific data is available for the product for chronic exposure symptoms. The persistent activity of CYDECTIN POUR-ON FOR CATTLE & RED DEER prevents the development of viable cattle tick (Rhipicephalus (Boophilus) microplus) for 21 days after treatment. We comply with the HONcode standard for trustworthy health information -. Indication of immediate medical attention and special I agree that Cydectin is a last resort wormer used when your worm "herd" has built a resistance to the other wormers out there. The Do not contaminate water by direct application or by improper disposal of drug containers. Figure 1. Varying weather conditions, including rainfall, do not affect the efficacy of Cydectin Pour-On. Cydectin® Pour-On SDS US 923917 Version #: 01 Revision date: - Issue date: 04-May-2015 4 / 7 Though off label Cydectin Pouron is an accepted and widely used med for poultry and caged birds. Moxidectin binds selectively and with high affinity to glutamate-gated chloride ion channels which are critical to the function of invertebrate nerve and muscle cells. Moxidectin is an endectocide in the milbemycin chemical class which shares the distinctive mode of action characteristic of macrocyclic lactones. Administer 1 mL per 11 lb (1 mL per 5 kg) body weight into the mouth of the sheep, ... HUMAN WARNINGS: Not for use in humans. Do not apply to areas of skin with mange scabs, skin lesions, mud or manure. CYDECTIN INJECTION FOR CATTLE is effective against … my choice of dewormers is Cydectin injectable given orally. Not For Use in Humans. If irritation or any other symptom attributable to exposure to this product persists, consult your physician. Killing H. bovis when they are in the vertebral canal may cause staggering or hindlimb paralysis. Keep this and all drugs out of the reach of children. Figure 3. Do not use in calves to be processed for veal. Keep this and all drugs out of the reach of children. H412 Harmful to aquatic life with long lasting effects. ADMINISTRATION: CYDECTIN Oral Drench is ready-to-use. Check dose rates and equipment before drenching. Side effects increased as the dose was raised, so there is no sense in going crazy and using a higher dose. Other side effects may include scratching, application site reactions, rubbing, lethargy, hyperactivity, uncoordinated walking, trembling, excessive salivation, increased drinking, and coughing or gagging. Not for human use. CYDECTIN (moxidectin) Pour-On is specially formulated to allow moxidectin to be absorbed through the skin and distributed internally to the areas of the body affected by endo- and/or ectoparasitism. Cydectin Oral Drench for Sheep Indications. Cydectin Oral Drench is ready-to-use. Data sources include IBM Watson Micromedex (updated 2 Nov 2020), Cerner Multum™ (updated 2 Nov 2020), ASHP (updated 23 Oct 2020) and others. Boehringer Ingelheim Vetmedica, Inc. Boehringer Ingelheim Vetmedica, Inc. CYDECTIN moxidectin moxidectin moxidectin NADA 141-220, Approved by FDA Injectable Solution for Beef and Nonlactating Dairy Cattle Antiparasitic Contains 10 mg moxidectin/mL Not for use in female dairy cattle 20 months of age or older (including dry dairy cows), veal calves, and calves less than 8 weeks of age. Consult your veterinarian for assistance in the diagnosis, treatment, and control of parasitism. The table below will assist in the calculation of the appropriate volume of drench in 1.0 mL increments and it must be administered based on the weight of animal being treated. The effectiveness of preoperative albendazole has been studied in a randomized comparison with no treatment in 84 patients with isolated hydatid cysts of the liver. 2003). Do not contaminate water by direct application or by improper disposal of drug containers. An aid in the control of selenium responsive conditions. This product has been formulated specifically for topical use in cattle and should not be used in other animal species or by other routes of administration as adverse reactions may occur. Moxidectin is a drug that is used to treat parasites in dogs, cats, and large farm animals. The table below will assist in the calculation of the appropriate volume of drench in 1.0 mL increments and it must be administered based on the weight of animal being treated. Not For Use In Humans. In breeding animals (bulls and cows in estrous and during early, mid and late pregnancy), treatment with three times the recommended dose level had no effect on breeding performance. Information on toxicological effects Acute toxicity Not expected to be acutely toxic. Cydectin 2% LA acts by interfering with chloride channel-mediated neurotransmission in the parasite. Newborn calves similarly showed no toxic signs when treated with up to three times the recommended dose level within 12 hours of birth and nursing from cows concurrently treated with the recommended dose level of Cydectin Pour-On. Dispose of containers in an approved landfill or by incineration. Cattle should be treated as soon as possible after heel fly (warble fly) season to avoid this potential problem. Cydectin Pour-On is available in five convenient container sizes. When used according to label directions, neither a pre-slaughter drug withdrawal period nor a milk discard time are required. Cydectin Long Acting Injection for Sheep, for the treatment and control of roundworms, nasal bot and itchmite in sheep. Warning: Not For Use In Humans. WHAT IS CYDECTIN ® INJECTION FOR CATTLE?. Cydectin LA is an endectocide in the milbemycin chemical class which shares the distinctive mode of action characteristic of macrocyclic lactones. Haemonchus contortus - Adult and L 4 HUMAN WARNINGS: Not for use in humans. In case of accidental eye contact, flush eyes with copious amounts of water. Hepatobiliary Adverse Reactions. Cydectin 2% LA Oral Drench for Sheep is a ready-to-use solution containing 0.1% Cydectin 2% LA. It has also been used off label to treat adult heartworms. Symptoms associated with serotonin syndrome may include the following combination of signs and symptoms: mental status changes (e.g., agitation, hallucinations, delirium, and coma), autonomic instability (e.g., tachycardia, labile blood pressure, dizziness, diaphoresis, flushing, hyperthermia), neuromuscular symptoms (e.g., tremor, rigidity, myoclonus, hyperreflexia, incoordination), seizures, … It is contraindicated in sick, debilitated, or underweight animals. Cattle treated with Cydectin Pour-On at the end of fly season can be re-treated during the winter without danger of grub-related reactions. Moxidectin acts by interfering with chloride channel-mediated neurotransmission in the parasite. bovis). In case of accidental skin contact and/or clothing contamination, wash skin thoroughly with … (16.91 fl oz/500 mL and 33.81 fl oz/1 L Bottles), Large Conventional Containers (84.54 fl oz/2.5 L and 169 fl oz/5 L. Not For Use In Humans. Precautionary statement(s) Prevention P273 Avoid release to the environment. Keep this and all drugs out of the reach of children. Not for use in humans. Moxidectin is a second generation macrocyclic lactone (ML) with potent endectocide activity. Efficacy below 90% was observed in some Ostertagia ostertagi persistent activity studies at 21 and 28 days posttreatment. Select one or more newsletters to continue. It has been established in laboratory tests that moxidectin may temporarily affect dung beetle reproduction; however, field studies indicate no long-term effects. This is a disease that is easily spread from animal to humans and is the world’s most widespread zoonosis. Dosage Form: FOR ANIMAL USE ONLY, For Treatment of Infections and Infestations Due to Internal and External Parasites of Beef and Dairy Cattle. Cydectin is a registered trademark of Boehringer Ingelheim Vetmedica, Inc. This topical, ready-to-use formula works to control mites, lice, grubs, lungworms, and … Phone: (02)9899 0444 Page 2 of 4 Issued: 4 Jul 2002 Revision 5 ll HEALTH HAZARD DATA Health Effects: No specific data is available for the product for chronic exposure symptoms. To obtain a copy of the material safety data sheet (MSDS) which provides more detailed occupational safety information or to report adverse reactions attributable to exposure to this product, call 1-800-422-9874. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. CYDECTIN INJECTION FOR CATTLE delivers the trusted power of moxidectin, the most trusted, potent and persistent “mectin, in a water based, non-sting formulation; CYDECTIN INJECTION FOR CATTLE provides broad spectrum control of internal and external parasites. Side-effects Lethargy Vomiting Diarrhea Loss of appetite Stumbling Cydectin Solution may also cause side-effects not listed here. Consult your veterinarian for assistance in the diagnosis, treatment and control of parasitism. A well-controlled U.S. study has demonstrated an adequate margin of safety to allow treatment of sheep four months of age and older with Cydectin Oral Drench. Squeeze-Measure-Pour System 16.91 fl oz/500 mL and 33.81 fl oz/1 L Bottles), Large Conventional Containers (84.54 fl oz/2.5 L and 169 fl oz/5 LBottles and 338 fl oz/10 L Cubetainer). Not for use in humans. The 16.91 fl oz/500 mL (NDC 0010-3843-01) and 33.81 fl oz/1 L (NDC 0010-3843-02) are packaged in specially-designed squeeze-measure-pour polyethylene bottles. I have trialled on sacrificial roosters up to 2 ml and no ill effects. To obtain a copy of the material safety data sheet (MSDS) which provides more detailed occupational safety information or to report adverse reactions attributable to exposure to this product, call 1-866-638-2226. HUMAN WARNINGS. FREE Shipping. Side Effects & Adverse Reactions. If you have any questions, please contact your veterinarian. Eight subjects had dizziness or somnolence/lethargy (one in the placebo group, two who took 9 mg, one who took 18 mg, and four who took 36 mg). This interferes with neurotransmission resulting in paralysis and elimination of the parasite. 09. CYDECTIN Injectable is specially formulated to allow moxidectin to be absorbed from the site of injection and distributed internally to the areas of the body affected by endo- and/or ectoparasitism. Target Species: Cattle Source: ESR 2013 Annual Surveillance Report. Store product at or below room temperature. In case of ingestion do not induce vomiting and seek medical attention immediately. Virbac’s latest addition to the Cydectin franchise, Cydectin Platinum, offers the potency and the persistency of Moxidectin as well as the broad spectrum activity of dual actives.
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